Whole Genome Amplification Market

Whole Genome Amplification Market

Whole Genome Amplification Market: Advent of Lysing Techniques & Primer Technologies to Advocate Preference for Single-cell WGA: Analysis 2013 - 2017 and Opportunity Assessment 2018 - 2028

  • XPLREP2398

  • June, 2018

  • 250 Pages

  • Medical Equipments

Single-Cell Whole Genome Amplification to Sweep the Whole Genome Amplification Market

As per a report published on XploreMR, the global whole genome amplification market is expected to grow on explicit grounds between 2020 and 2030. The lysing techniques and primer technologies have been witnessing massive advancements. This trend is acting as a booster to whole cell genome amplification market.  Single cell whole genome amplification is the most preferred one. It is used for examining sequence information in line with optimal next generation technologies, that too, from single cell.

The current scenario is such that screening for various neurological and developmental genetic disorders heavily depends on single-cell whole genome amplification. Due to high-resolution view offered, the adoption is expected to continue immunology, cancer research, microbiology, neurobiology, and tissue mosaicism.

Sigma-Aldrich’s GenomePlex WGA4 kits have been designed keeping single-cell WGA in mind. The other kits serve the purpose for a constellation of cells as well. GE Healthcare, QIAGEN NV are the other companies working with single-cell kits.

Whole Genome Amplification Market Dynamics

The US FDA has issued guidelines like “510-K” with the objective of focusing more on safety. The stringent rules as well as regulations with regards to enhancement in precision and efficiency are compelling the key players to think atleast twice before putting forth any claims pertaining to whole genome amplification.

Moreover, the “Pre-Market Approval” section of the US FDA has mandated the kits manufacturers to register as well as notify them in advance (atleast 90 days) of their idea of promoting their product. These happenings are bound to ascertain authenticity on the count of market players and also ring a warning signal to the new players.

Custom Product Offerings: The need of the Hour

The custom requirements ask for exclusive time management that is sternly based on vendors’ choices. Moreover, the vendors demand tried-and-tested solutions to suffice their custom reagent requirements so that they could save on both – effort and time in validating custom products before using them in the critical experiments. As such, it could be inferred that made-to-order products/kits are likely to hold the hopes high for whole genome amplification market in the near future.

Whole Genome Amplification Market Challenges

Whole Genome Amplification (WGA) implies extracting, amplifying, and sequencing. PCR whole genome amplification involves STR expansions and contractions, single base-pair mutations, and under-represented and biased loci. Though PCR whole genome amplification gives accurate results, the same is doubtful about REPLI-g technology, as there is minimal locus bias at the time of amplification. This factor ought to restrain the market in the years to come.

Insights: Product- , Application-, and End-User-wise

As of now, there are single cell WGA kits, complete WGA kits, WGA re-amplification kits, WGA & chip DNA kit. The application areas include disease diagnosis, forensics, research, agriculture & veterinary, drug discovery & development. The end-users constitute pharma & biotech companies, contract research, organizations, hospitals & clinics, research & academic institutes.

The single cell WGAs are in great demand as far as disease diagnosis, research, and forensics are concerned. With pet and livestock care picking up faster than before, the “agriculture & veterinary” sector is also expected to go great guns herein.

Insights: Region-wise

The global whole genome amplification market constitutes North America (Canada, US), Eastern Europe (Russia and Poland), Western Europe (Luxembourg, The Netherlands, Belgium, Nordic countries, Italy, Spain, France, UK, Germany), Asia-Pacific (New Zealand, Australia, ASEAN, Japan, India, China), MEA (North Africa, Southern Africa, GCC), and Latin America (Chile, Peru, Brazil, Mexico, and others).

North America leads from the front due to good amount of GDP being diverted to healthcare, followed by Europe. Asia-Pacific is slowly picking up with the governments shifting their gear towards healthcare.

Competitive Landscape

The key players in the whole genome amplification market include QIAGEN NV, GE Healthcare, and Sigma-Aldrich Corporation.

Important Questions Answered

  • What is the growth potential of the Whole Genome Amplification Market?
  • Which company is currently leading the Whole Genome Amplification Market? Will the company continue with the winning streak during the forecast period?
  • What are the top strategies that players are expected to adopt in the years to come?
  • Which regional market is anticipated to secure the highest market share?
  • How will the competitive landscape change in future?
  • What do players need to do to adapt to future competitive changes?
  • What will be the total production and consumption with regards to Whole Genome Amplification by 2030?
  • Which are the key upcoming technologies? How will they impact the Whole Genome Amplification Market?
  • Which product segment is expected to show the highest CAGR?
  • Which application is forecast to gain the biggest market share?

Highlights of TOC:

Overview: Along with a broad overview of the Whole Genome Amplification Market, this section gives an overview of the report to give an idea about the nature and contents of the research study.

Market Dynamics: Here, the authors of the report have comprehensively discussed about key drivers, restraints, challenges, trends, and opportunities of the Whole Genome Amplification Market.

Product Segments: This part of the report throws light on the market growth of several types of products sold by leading companies.

Application Segments: The analysts authoring the report have deeply assessed the market potential of key applications and identified future opportunities they are expected to create in the Whole Genome Amplification Market.

Geographical Segments: Each regional market is carefully looked into for understanding its current and future growth scenarios.

Company Profiles: Top players of the Whole Genome Amplification Market are thoroughly profiled in the report based on their market share, market served, products, applications, regional growth, and other factors.

Global Whole Genome Amplification Market

The global Whole genome amplification market report provides analysis and insights on Whole genome amplification kits and consumables. Commercially available Whole genome amplification kits are based on Single cell WGA kits, Complete WGA Kit, WGA Reamplification Kit, WGA & Chip DNA Kit and others. Increasing demand for technologically advanced methods in sample preparation, extraction, amplification and testing for nucleic acid and the strategic agreements of manufacturers with leading research institutes to boost research activities in molecular biology field play a vital role for fueling the demand of Whole genome amplification. These Whole genome amplification kits can be used in both clinical diagnostics as well as for research applications. Applications such as agricultural and veterinary animal cell DNA testing, viral and bacterial infectious diseases, drug discovery & development, cancerous diseases, forensic testing, genetically related diseases and paternity testing/HLA typing coupled with rising awareness is predicted to increase usages of whole genome amplification worldwide. This is expected to bolster growth of the Whole genome amplification market over the forecast period.

Global Healthcare Sector Outlook

Despite the economic and political uncertainty in the recent past, the global healthcare industry has been receiving positive nudges from reformative and technological disruptions in medical devices, pharmaceuticals and biotech, in-vitro diagnostics, and medical imaging. Key markets across the world are facing a massive rise in demand for critical care services that are pushing global healthcare spending levels to unimaginable limits.

A rapidly multiplying geriatric population; increasing prevalence of chronic ailments such as cancer and cardiac disease; growing awareness among patients; and heavy investments in clinical innovation are just some of the factors that are impacting the performance of the global healthcare industry. Proactive measures such as healthcare cost containment, primary care delivery, innovation in medical procedures (3-D printing, blockchain, and robotic surgery to name a few), safe and effective drug delivery, and well-defined healthcare regulatory compliance models are targeted at placing the sector on a high growth trajectory across key regional markets.

Research Methodology

XploreMR utilizes a triangulation methodology that is primarily based on experimental techniques such as patient-level data, to obtain precise market estimations and insights on Molecule and Drug Classes, API Formulations and preferred modes of administration. Bottom-up approach is always used to obtain insightful data for the specific country/regions. The country specific data is again analysed to derive data at a global level. This methodology ensures high quality and accuracy of information.

Secondary research is used at the initial phase to identify the age specific disease epidemiology, diagnosis rate and treatment pattern, as per disease indications. Each piece of information is eventually analysed during the entire research project which builds a strong base for the primary research information.

Primary research participants include demand-side users such as key opinion leaders, physicians, surgeons, nursing managers, clinical specialists who provide valuable insights on trends and clinical application of the drugs, key treatment patterns, adoption rate, and compliance rate.

Quantitative and qualitative assessment of basic factors driving demand, economic factors/cycles and growth rates and strategies utilized by key players in the market is analysed in detail while forecasting, in order to project Year-on-Year growth rates. These Y-o-Y growth projections are checked and aligned as per industry/product lifecycle and further utilized to develop market numbers at a holistic level.

On the other hand, we also analyse various companies annual reports, investor presentations, SEC filings, 10k reports and press release operating in this market segment to fetch substantial information about the market size, trends, opportunity, drivers, restraints and to analyse key players and their market shares. Key companies are segmented at Tier level based on their revenues, product portfolio and presence.

Please note that these are the partial steps that are being followed while developing the market size. Besides this, forecasting will be done based on our internal proprietary model which also uses different macro-economic factors such as per capita healthcare expenditure, disposable income, industry based demand driving factors impacting the market and its forecast trends apart from disease related factors.

Market Taxonomy

 By Product Type

By Application

By End User

By Region

  • Single Cell WGA Kit
  • Complete WGA Kit
  • WGA Reamplification Kit  
  • WGA & Chip DNA Kit
  • Others
  • Drug Discovery & Development  
  • Disease Diagnosis
  • Agriculture & Veterinary
  • Research
  • Forensics
  • Others
  • Pharma & Biotech Companies
  • Hospitals & Clinics
  • Contract Research
  • Organizations
  • Research & Academic Institutes  
  • Others
  • North America
  • Latin America
  • Western Europe  
  • Eastern Europe
  • APEJ
  • MEA
  • Japan
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Whole Genome Amplification Market: Advent of Lysing Techniques & Primer Technologies to Advocate Preference for Single-cell WGA: Analysis 2013 - 2017 and Opportunity Assessment 2018 - 2028
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